Marie Doumic-Jauffret

(INRIA, France)

Aggregation/fragmentation models for protein polymerization

Abnormal protein polymerization is at the origin of a number of neuro-degenerative diseases, e.g. Prion (Madcow), Huntington or Alzheimer diseases. This phenomenon can be described mathematically either in a discrete or in a continuous setting, by equations of fragmentation-coagulation type. We review here some results and some open problems on the study of prion proliferation equations.